Monday, December 30, 2019

Character Analysis Of Mice And Men - 910 Words

John Steinbeck sets the scene of his novella, Of Mice and Men, in the Salinas River Valley, a few miles south of Soledad. The time period of the novella is the 1930’s during the Great Depression. The Great Depression began in 1929 after the U.S. had a major financial crisis. People lost all of their money and their homes when the stock market crashed. Many men became migrant farm workers who would travel from farm to farm, working for just enough money for food and a few belongings. John Steinbeck grew up in the Salinas River Valley during the Depression. In his novella, of Mice and Men, Steinbeck uses the characters Candy, Curley’s wife, and Crooks to prove people will do anything to stop being lonely. To begin, Steinbeck uses the†¦show more content†¦Candy shows people will do anything to not be lonely. Furthermore, Steinbeck uses Curley’s wife to show how people will do anything to not be lonely. Even though Curley’s wife is married, she flirts with the other men on the farm. Curley is a boxer and wears expensive clothes. His father is the boss on the farm and has a lot of money. Curley’s wife tries to talk to the boys but they don’t trust her. She says, â€Å"Why can’t I talk to you? I never get to talk to nobody. I get awful lonely† (Steinbeck 86). This quote shows that no one ever tries or wants to talk to her. Curley’s wife complains to Lennie about how lonely she is and that she just wants to talk to people. As the book continues, she explains to Lennie why she never gets to talk to anyone. She says, â€Å"You can talk to people, but I can’t talk to nobody but Curley. Else he gets mad† (Steinbeck 87). This quote shows that Curley is very controlling over his wife and only lets her talk to him. Curley’s wife talks to Lennie even though he is very intimidating. She is desperate to talk to anyone so she flirts with Lennie and the other men to get their attention. Lastly, Steinbeck uses Crooks to show the things people are willing to do to not be lonely. Crooks is the black crippled stable buck who works on the farm. He is the only black man for miles and has no one to talk with, or to be his friend. Crooks tells Lennie, â€Å"A guy needs somebody - to be near him . . . A guy goes nuts if heShow MoreRelatedOf Mice And Men : Character Analysis1742 Words   |  7 PagesOf Mice and Men: Character Analysis John Ernst Steinbeck Jr. was an American author wrote many novels including one of his most famous, Of Mice and Men. Of Mice and Men teaches many lessons about the nature of human existence. Each relationship grows throughout this short story and end with a dramatic experience. All of the characters, including Lennie, George, Crooks, and Curley’s wife, admit, at one time or another, to having a profound sense of isolation, seclusion and loneliness. The authorRead MoreCharacter Analysis in of Mice and Men2098 Words   |  9 PagesCHARACTER ANALYSIS George George is the second main character and one of the protagonist after Lennie in Of Mice and Men. When Lennie gets into trouble, He always helps him find a solution or get away, though Lennie’s size combined with his mental handicap caused problems frequently. He is also a planner, telling Lennie where he should go if there is trouble on the ranch. To make the dream which is owing a ten-acre farm becomes a reality, He’s competent to work hard. Unlike theRead MoreOf Mice And Men Character Analysis1137 Words   |  5 PagesThe novel, Of Mice and Men, by John Steinbeck, written in 1937. Was placed in The Great Depression, in California. Of Mice and Men is a novel about two men named George and Lennie who have a dream to own a house on the land and have animals and a farm to themselves and Lennie is addicted to soft things. Lennie is all about tending rabbits in this dream they have. It is very rare for a two men to travel together in this time period. Everybodys working for themselves to get money for themselvesRead MoreOf Mice And Men Character Analysis839 Words   |  4 PagesThe Friendship of Mice Friendship is a value that everyone should clearly understand the meaning of. Guidance of others through obstacles and making helpful choices. However, there are highs and lows of each friendship, people should always be there for each other as human beings no matter what color you are or what disability you might have. In the novella Of Mice and Men, the author develops the importance of friendships and companionships. The author, John Steinbeck, illustrates the value ofRead MoreOf Mice And Men Character Analysis Essay710 Words   |  3 PagesEvery story focuses on the main characters, but it is not only the protagonist or protagonists that make the plot interesting, the ones who make it interesting are the background characters. In the novel Of Mice and Men, written by John Steinbeck, Steinbeck provides the characters on the ranch diverse roles. The book Of Mice and Men takes place during The Great Depression, focusing on two characters, a pair of friends, with the names of George and Lennie. Throughout the book Steinbeck narrates GeorgeRead MoreOf Mice And Men Curley Character Analysis1277 Words   |  6 PagesThe mystery, the troublemaker, the mischief maker, all these words are used to describe a single person, the wife of the man named Curley. This woman whose name is not ever mentioned in the book, is a character from the book Of Mice and Men by John Steinbeck. The presence of this woman alone caused mischief, distrust, a bit of rivalry, and mishap on the farm among the coworkers of her husband. This trouble is demonstrated when Slim says to Curley,  ¨ Well, you been askin ´ me too often. I m gettin ´Read MoreOf Mice And Men Loneliness Character Analysis863 Words   |  4 Pageslife? Inside the novel of Mice and Men by John Steinbeck, loneliness was shown by many of the characters including Curley’s wife when she felt like she had no one there, not even her husband, Candy when his dog passed away, and many other characters. Loneliness is a big theme in the novel and affects many of the characters in many different ways. Three main characters who were mostly affected by loneliness in this novel are Crooks, Curley’s wife, and George. One character that experiences lonelinessRead MoreOf Mice and Men by John Steinbeck973 Words   |  4 Pagescanals and working beside men similar to characters in his novels. 2. In a discussion John Steinbeck said, I worked in the same country that the story is laid in. The characters are composites to a certain extent. Lennie was a real person. Hes in an insane asylum in California right now. I worked alongside him for many weeks . . .† (Parini 27) a. During the interview Steinbeck told his personal experiences that permitted him to write and construct the novel Of Mice and Men. II. Proof of Thesis Read MoreAnalysis of Of Mice and Men by John Steinbeck1493 Words   |  6 PagesAnalysis of ‘Of Mice and Men by John Steinbeck ‘Of Mice And Men by John Steinbeck is a classic novel, tragedy, written in a social tone. The authorial attitude is idyllic, however, as the story develops it changes into skeptic. It is evident that Steinbeck knew the setting and places he is writing about. In my opinion Steinbeck drew the subject matter from his own experience of working on ranches, he was interested in special kinds of relationships among men working on ranches with him. ThereRead MoreEssay about Analysis of ‘Of Mice and Men by John Steinbeck 1488 Words   |  6 PagesAnalysis of ‘Of Mice and Men by John Steinbeck ‘Of Mice And Men by John Steinbeck is a classic novel, tragedy, written in a social tone. The authorial attitude is idyllic, however, as the story develops it changes into skeptic. It is evident that Steinbeck knew the setting and places he is writing about.

Saturday, December 21, 2019

We Need new Ways of Security to Attack Terrorism Essay

Unfortunately, in America today, we are confronted with a major issue, insecurity of transportation caused by terrorism. Terrorism today has killed millions of Americans and we are forced to act on these actions. We can’t sit and watch as we are attacked, and people are killed in our own country. We must develop new methods that provide better safety for all passengers. It is very clear that the precautions we are taking now are inefficient and unaffordable. That is why I believe racial profiling is a harsh but, necessary part in keeping America safe. Despite the hostility of racial profiling it is constitutional, it saves money, and most importantly it has worked. In America, the constitution is the final law of the land. The†¦show more content†¦Under the constitution they have created the Equal Protection Clause which states,† the government shall not deny to any person within its jurisdiction the equal protection of it laws.†(Public Discourse) By using racial profiling, don’t we equally protect all Americans from all threats? By targeting these races and cultures it makes our airliners safer for everyone including the people being searched. Some people argue that this is an act of racism and will terrorize Muslim or whoever is being targeted with bigotry and mistreatment. Unfortunately, all security system are run by humans so it can’t be perfect because many people have bias and abuse there positions of power, but this is true for all position of power, and can’t be controlled. With all plans there are some consequences but, there are measures that can be put into effect that control this mistreat ment with care guidelines on how to treat those people who they have pulled aside. Not only does it fall under, but it also could save a lot of money. Most people would agree that money talks, no one can argue with that. That is just how our society is today. Looking at the numbers, searching for terrorist by race extremely more efficient than searching everyone in the airport like they do today with the body scanners. They would need less scanner and less TSA workers resulting in a greater revenue for the airports. One of the mainShow MoreRelatedEconomic Impact Of Terrorism On Terrorism1645 Words   |  7 Pages Economic Impact of Terrorism Micheal Bonnett Govt/480 December 8, 2014 Thomas Brown Abstract The impact on the economy from terrorist attacks affects everyone in our country and ones we do trade with on a daily bases. When terrorist attack countries they are trying to disrupt the economy and excite fear in as many people as possible to meet the needs of what the terrorist group is looking to achieve. Without a definitive definition on what terrorism is it will continue to adaptRead MoreTerrorism : Terrorism And Terrorism1126 Words   |  5 PagesTerrorism Have you ever had a fear for your family, your town, your country, or your world. How about the fear to have everything taken from you, destroyed, and not caring if it has hurt you or not? What about your fear and pain is, and can be someone else’s happiness? The fear of you being terrorized? That is terrorism. Someone else bringing fear and terrorizing you. That is a terrorist’s goal. Terrorism is common and is very difficult to stop. The government promises protection for the peopleRead MoreTerrorism And Terrorism : Terrorism1231 Words   |  5 Pages Terrorism is a common term used in the media and news everyday, especially in the United States. We are in a constant battle against ‘terrorism’, â€Å"Counterterrorism has to be woven into the everyday workings of every department. It should be included on the agenda of every meeting†¦Ã¢â‚¬  (Kelling Bratton, 2006). Terrorism and How to Respond All terrorism is criminal but not all criminals are terrorists. Terrorism unlike most crimes has a political agenda behind it. Many terrorists are involved withRead MoreInternational Terrorism And Domestic Terrorism Essay1467 Words   |  6 PagesTerrorism is all over the current headlines, but some of the very worst attacks happened 15 years ago in the United States; this occurrence brought around many changes of policies inside the U.S. but also policies in the U.S. regarding other foreign countries. It brings fear and terror to many of its victims and is an extremely dangerous national threat. There are mainly two kinds of terrorism that people can be affected by: International terrorism and domestic terrorism. Both of these can be describedRead MoreA Paper on Britains Security Position1337 Words   |  5 PagesBritains Security Position. Today, Britain faces a different and more complex range of threats from a myriad of sources. These include terrorism, cyber-attack, unconventional attacks using chemical, nuclear or biological weapons, as well as large scale accidents or natural hazards. In this briefing paper, we will discuss what Britains distinctive role should be in the coming years, the future about all of these and how can the UK get prepared. We will suggest strategies for UK security over theRead MoreCyber Terrorism And Threats Of Information System1688 Words   |  7 PagesCyber-Terrorism and Threats to Information System National security has been top priority of the United States after World War II. This is due to the fact that the United States before this time was relatively an isolationist country with no influence in the world. As a result national security was not important, this changed post World War II. The United States found themselves among the top, overnight they went from being new and not listened to, to becoming one of the major players in the worldRead MoreRole Of The Department Of Homeland Security1659 Words   |  7 Pagesterrorist attacks in the history of the United States . The creation of many anti-terrorism organizations was a clear message that this threat is beyond a single military or intelligence capacity. Our citizens demanded a strong response that would prevent any future terrorist threat. President Bush created the Department of Homeland Security as the key agency responsible for all anti-terrorism activities to protect our homeland. Government officials and law make rs introduced anti-terrorism laws andRead MoreTerrorism: September 11th, 2001 Essay870 Words   |  4 PagesStates it was a horrible day. Since then America has never been the same, but we cannot let that day change the way we think and act. Since the attack on September 11th, 2001 American citizens have been afraid of terrorists. The biggest contributor to this fear was 9/11, but that was not the only recent world attack. Terrorist attacks in Syria have also created fear, yet Syria is nowhere near the United States. While terrorism is definitely a threat, this concern is exaggerated. September 11th, 2001Read MoreTerrorism : Terrorism And Terrorism1586 Words   |  7 PagesIntroduction We are living in a world where there are so many global threats around us. World is not like heaven. We need to face many problems in our life. We have some global risk also. This year has been a notably rough year. Some of the worst threats make our people more worried. Many researchers and writers are writing about the biggest threats of the world. Several reports are also made to understand the recent global threats. In order to write something about the recentRead MoreOur Safeguards Against Cyberterrorism And What We Can Do About It1737 Words   |  7 PagesNathaniel Howard COMS 3053 Paper #1 Our Safeguards against Cyberterrorism In reality, attacks in cyber-space happen all the time. Over 20 million cyber-attacks happened within Utah in 2013 each day, and this was from Utah’s government websites, not including businesses. (â€Å"Fortis Blog†) Just imagine the various ways one could hack a website. Someone can even look up how to do it nowadays, and with at least half of the population in the U.S. using a computer, there are an untold number of people who

Friday, December 13, 2019

John Locke Provisos Essay Free Essays

John Locke was an English philosopher who had the thought that all people have natural rights. Their natural rights included that of life. autonomy and belongings and the thought of these rights being held by each person is frequently said to be the primary influence of the American Declaration of Independence. We will write a custom essay sample on John Locke Provisos Essay or any similar topic only for you Order Now Locke farther explains his principle behind natural rights in Two Treatises of Government and peculiarly belongings right in his â€Å"Provisos. † saying the conditions the brand belongings populace or private. Locke’s â€Å"Provisos† discusses the thought that belongings becomes private when a individual labours upon the belongings. His logical thinking that the land becomes the person’s private belongings is that a individual has the right to the fruits of his labour. and he besides has the right to the resource that bore his fruits. in this instance the belongings. As Locke says. â€Å"He by his labour does. as it were. envelop it from the common† ( page 437 ) . By this he means that by tuging over the land. the land is taken off from the remainder of society. the common. and becomes the private belongings of the person. Locke besides believes that â€Å"as much as a adult male tills. workss. improves. cultivates. and can utilize the merchandise of. so much is his property† ( page 437 ) . In this. he is saying that a adult male can have every bit much as can be utile to him ; claiming belongings in surplus and non being able to do it productive is incorrect because the belongings will so travel to blow alternatively of bearing fruit. This is incorrect because â€Å"nothing was made by God for adult male to botch or destroy† ( page 436 ) and holding land lying to waste is along the same lines as destroying the land. This thought from Locke’s â€Å"Provisos† follows from his thought of general belongings rights. He believes that land that has non been influenced by an individual’s labour is land available for all of society. Man should still esteem the land and non work it. but â€Å"were it non for the corruptness and ferociousness of pervert adult male. there would be no demand of any other. no necessity that work forces should divide from this great and natural community† ( page 441 ) . However because world can non be trusted. Locke believes that one time a adult male does set forth attempt to better a piece of belongings. that land and the merchandises of it belong to him. Although that land might belong to one adult male. it is still profiting the remainder of society because â€Å"the commissariats functioning to the support of human life produced by one acre of enclosed and cultivated land are ten times more than those which are yielded by an acre of land of an equal profusion lying waste in common† ( page 437 ) . This is similar to the manner in which both a husbandman and society benefits from his crop. The husbandman and society both can have nutriment from his crop and what crop goes to the remainder of society. he is repaid for. which allows him to go on seeding seeds that will go on to foster the common. A state of affairs of private belongings that would conflict with one of the Lockean provision is belongings that is acclaimed through coercing Native Americans to hold with the American imposts that were being imposed and the American regulation. or to go forth. such as with the Indian Removal Act that was signed into jurisprudence in 1830. The Native Americans had worked the land and made it suited to back up their life style and in the quest to accomplish Manifest Destiny. nil would impede the determined heads of the Americans. Harmonizing to Locke. the land truly belonged to the Native Americans because they had labored on the land to do it comfortable. They did non work it ; they used the resources sagely and nil went to blow with their minimalist life style. With the Indian Removal Act that President Andrew Jackson signed into consequence. all Native Americans had to be relocated to countries west of the Mississippi River. The Native Americans were removed on the footing that American colonisers needed the land and wanted to accomplish Manifest Destiny. Another state of affairs affecting private belongings that would go against one of the Lockean provision would be that of the authorities prehending land due to unpaid revenue enhancements. In this state of affairs. a husbandman could hold yielded a big crop. but the demand for his harvest declined greatly to the point that he is unable to do a big adequate net income to pay his revenue enhancements. This could fall into a form for many old ages to come. finally making the point that the authorities can no longer merely maintain seting the husbandman into more debt. The husbandman would hold to claim bankruptcy and the authorities would prehend his land. This would go against Locke’s thought that the land a adult male plant. is his. The husbandman was making the best he could. was profiting society. and ne’er consented to losing his right to his land. but the authorities took it away anyhow. I believe that Locke right draws the line on private belongings because we have the right over our ain organic structures. and if the work of those organic structures can unite with resources to make something. so we have the right to claim that merchandise and the resources we used to do it. No 1 else put forth the attempt and therefore the fruit of our attempts are ours. I believe that difficult work deserves reward and that wages is the right to the merchandise. As Locke says. â€Å"The labour of his organic structure and the work of his custodies. we may state. are properly his† ( page 436 ) . How to cite John Locke Provisos Essay, Essay examples

Thursday, December 5, 2019

Health Variation Left Heart Failure

Question: Discuss about the Health Variation for Left Heart Failure. Answer: 1: This case study is regarding Mrs. Brown who is 78 years old and has been admitted to the Emergency department at 6 am after waking up with severe breathlessness. The patient has a history of heart failure, which was diagnosed two years ago. On physical examination, she was diagnosed with atrial fibrillation, which suggested acute exacerbation of left heart failure. The inefficient pumping of the heart for maintaining the blood flow in the body leads to congestive left heart failure. The clinical manifestations of this disease include pulmonary edema, fatigue, shortness of breath and swelling feet and ankles. The patient also had severe dyspnoea that was apparent by the elevated respiratory rate of 24 breaths/ min and had an abnormal pulse rate of 110 beats/minute. It is essential to know the pathogenesis of this condition, which is leading towards these manifestations of the patient (Rosenkranz et al., 2015). The cause of heart failure is due to the inefficiency of the muscles of the heart along with other conditions such as cardiac amyloidosis. For the patients like Mrs. Brown, the normal Frank-starling mechanism fails and due to this, the contraction of muscles become difficult and leads to a decreased cardiac output. The changes in neurohumoral status, blood volume and vascular function arise due to cardiac dysfunctions (Park et al., 2012). The vascular and cardiac changes associated with left heart failure are the following: Reduced ejection fraction in case of systolic dysfunction and ventricular dilation impaired filling in the case of diastolic dysfunction Increase in diastolic pressure and decrease in cardiac output Vascular alterations comprise impaired arterial pressure and increased volume of blood (Steinberg et al., 2012). In the patients with heart failure, a decreased output is seen due to the reduction in the stroke volume because of either diastolic or systolic dysfunction. In the case of diastolic dysfunction, stiffening of ventricle occurs along with the impairing of normal ventricular filling. High ventricular end-pressure and decreased ejection of blood results due to reduced ventricular filling. On the other hand, systolic dysfunction results due to the loss of contractility followed by acute myocardial infarction. This compensatory mechanism is initiated by using the Frank-Starling mechanism for increasing stroke volume (Reil et al., 2013). The volume of blood in left heart failure is enhanced due to the reduced renal perfusion, which leads to the more fluid retention and reduced output of urine. In addition, the activation of rennin-angiotensin system augments the secretion of aldosterone. The outcome is enhanced in the renal absorption of sodium and other fluids. The increased volume of blood helps in maintaining the cardiac output leads to an increase in the venous pressure resulting in systemic and pulmonary edema. For understanding this mechanism, there is a need to understand the cause of clinical manifestation of the patient in the present case study of the patient and plan treatment in order to reduce the volume of blood. The patient is also having a crackle sound at the base of each lung also suggest that she is experiencing pulmonary edema due to which she is not able to breathe properly (Rosenkranz et al., 2015). The neurohumoral response in the heart of the patients like Mrs. Brown takes place due to heart failure. It is concerned with the activation of the sympathetic nerves together with the release of atrial peptides and vasopressin. It results in venous constriction, vasoconstriction and increased volume of blood (Bath et al., 2016). All of these are the compensatory mechanisms for increasing ventricular filling and, but it frequently deteriorates the condition by enhancing the ventricular load and results in pulmonary congestion and edema. Hence, it is necessary to know the pathophysiology of heart failure for finding the rationale for every therapeutic intervention (Schwartzenberg et al., 2012). 2: For management of Mrs. Brown, the two high priority-nursing strategies are the following: Strategy for relieving pulmonary and dyspnoea: in order to manage acute shortness of breath, the nurse for providing relief from the symptoms of dyspnoea can administer diuretics. It will also be necessary to monitor closely the renal function, fluid balance and urine output in the patient. The output of urine can be assessed by indwelling urinary catheter but is should be restricted very soon as it results in infections of the urinary tract (McMurray et al., 2012). Strategy for managing the decreased cardiac output: As the patient is experiencing irregular rhythm of pulse along with an altered heart rate, it is essential to plan intervention that will help to reduce the workload of the heart and provide the patient hemodynamic stability. At first the nurses will assess the sounds of the heart and lungs. They will also monitor the blood pressure and perform diagnostic test. For improving the cardiac output, they will administer the cardiac glycoside agents. They will teach the patient to assume those positions, which will better expansion of the chest and along with improved pulmonary capacity. It is necessary to provide education to the patient regarding the pathophysiology of disease for managing the disease in a proper way (McHugh Ma, 2013). 3. a) IV furosenide: a loop diuretic pill helps in the prevention of reabsorption of water in the kidney by blocking potassium-chloride cotransporter. On the chloride binding site, competitive inhibition prevents the transport of sodium and reduces osmotic gradient for reabsorption of water throughout the nephron (Ali et al., 2014). Glyceryl trinitrate: It leads to the activation of guanylate cyclase enzyme and helps in stimulating the release of cyclic guanosine 3 5monophospate. It results in protein kinase dependent phosphorylation in the smoothy muscles and leads to dephosphorylation of of myosin chain of the smooth muscle (Viefhues et al., 2012). b) After giving Furosemide to the patient, the signs of allergic responses towards drugs will such as nausea, selling of face, kidney problem and jaundice will be will be checked by the nurse. As this drug is utilized for preventing the body to absorb excess salt, it might also result in electrolyte imbalance. Therefore, the nurses should check the signs of muscle cramp, dry mouth and thirst (Ali et al., 2014). Glyceryl trinitrate is used for the treatment of heart failure and angina. The nurses should take precautions prior to giving it to the patients having glaucoma, anaemia and low blood pressure. The nurses should also monitor the side effect of this drug in the patients having rapid heartbeat, rashes, dizziness, vomiting and swelling (Viefhues et al., 2012). C) The evaluation of therapeutic effect of the drug will be carried out by checking whether the symptoms of swelling and breathlessness have reduced or not. It will diminish the likelihood of heart attack. Glyceral nitrate is a vasodilator, and its therapeutic effects will be evaluated by checking if the patients are relived from the symptoms of heart failure (Viefhues et al., 2012). References Ali, Y., Parekh, A. M., Rao, R. K., Baig, M. R. (2014). Furosemide Induced Electrolyte Imbalance: A Real Danger of Overdiuresis in Patients with Heart Failure.Journal of International Translational Medicine,2(4), 482-484. Bath, P. M., Woodhouse, L., Krishnan, K., Anderson, C., Berge, E., Ford, G. A., ... in Acute Stroke Collaboration. (2016). Effect of Treatment Delay, Stroke Type, and Thrombolysis on the Effect of Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome after Acute Stroke: A Systematic Review and Meta-Analysis of Individual Patient from Randomised Trials.Stroke research and treatment,2016. Guazzi, M. (2014). Pulmonary hypertension in heart failure preserved ejection fraction prevalence, pathophysiology, and clinical perspectives.Circulation: Heart Failure,7(2), 367-377. McHugh, M. D., Ma, C. (2013). Hospital nursing and 30-day readmissions among Medicare patients with heart failure, acute myocardial infarction, and pneumonia.Medical care,51(1), 52. McMurray, J. J., Adamopoulos, S., Anker, S. D., Auricchio, A., Bhm, M., Dickstein, K., ... Jaarsma, T. (2012). ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012.European journal of heart failure,14(8), 803-869. Park, S. J., Milano, C. A., Tatooles, A. J., Rogers, J. G., Adamson, R. M., Steidley, D. E., ... Slaughter, M. S. (2012). Outcomes in advanced heart failure patients with left ventricular assist devices for destination therapy.Circulation: Heart Failure,5(2), 241-248. Reil, J. C., Hohl, M., Reil, G. H., Granzier, H. L., Kratz, M. T., Kazakov, A., ... Grber, S. (2013). Heart rate reduction by If-inhibition improves vascular stiffness and left ventricular systolic and diastolic function in a mouse model of heart failure with preserved ejection fraction.European heart journal,34(36), 2839-2849. Rosenkranz, S., Gibbs, J. S. R., Wachter, R., De Marco, T., Vonk-Noordegraaf, A., Vachiry, J. L. (2015). Left ventricular heart failure and pulmonary hypertension.European heart journal, ehv512. Schwartzenberg, S., Redfield, M. M., From, A. M., Sorajja, P., Nishimura, R. A., Borlaug, B. A. (2012). Effects of vasodilation in heart failure with preserved or reduced ejection fraction: implications of distinct pathophysiologies on response to therapy.Journal of the American College of Cardiology,59(5), 442-451. Steinberg, B. A., Zhao, X., Heidenreich, P. A., Peterson, E. D., Bhatt, D. L., Cannon, C. P., ... Fonarow, G. C. (2012). Trends in Patients Hospitalized with Heart Failure and Preserved Left Ventricular Ejection Fraction-Prevalence, Therapies, and Outcomes.Circulation, CIRCULATIONAHA-111. Tanai, E., Frantz, S. (2014). Pathophysiology of heart failure.Comprehensive Physiology Viefhues, H., Schoene, W., Rychlik, R., Kimchi, A., Lewis, B. S., Weiss, M. (Eds.). (2012).Chronic Heart Failure: I. Quality of Life II. Nitrate Therapy. Springer Science Business Media.